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Tech titans are hacking their bodies for a longer life: is there science behind their methods?

Ultra-wealthy entrepreneurs are using data, technology, and self-experimentation to optimize their bodies. This trend, known as humanmaxxing, involves efforts to maximize human potential and extend lifespans. Many of these protocols remain educated guesses rather than proven science.

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New reports identify specific figures like Bryan Johnson and Dave Asprey as leaders of the humanmaxxing movement.

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  1. Tech Figures Pursue Humanmaxxing and Biohacking for Longevity

    Ultra-wealthy entrepreneurs are using data, technology, and self-experimentation to optimize their bodies. This trend, known as humanmaxxing, involves efforts to maximize human potential and extend lifespans. Many of these protocols remain educated guesses rather than proven science.

    What's confirmed:

    • Bryan Johnson used a transplant drug to attempt to live longer but stopped due to side effects.
    • Biohacking involves using tools like glucose monitors and sleep trackers to optimize health through data and self-experimentation.

    Still unconfirmed:

    • Dave Asprey and Christian Angermayer are pushing the boundaries of human optimization.
    • Clinics such as Mount Med Resort in Austria and Clinique La Prairie in Switzerland provide biohacking services.
    • Billionaires are spending millions to reverse ageing.
    confidence 80%
  2. Tech Leaders Use Biology-Based Methods for Lifespan Extension

    Wealthy influencers and tech entrepreneurs are using supplements and drugs to extend their lives. Some of these practices are based on biological theory rather than clinical evidence. Efforts include the use of medications typically reserved for organ transplant patients.

    What's confirmed:

    • Nir Barzilai is the president of the Academy of Geroscience and a genetics researcher at Albert Einstein College of Medicine in New York City.
    • Bryan Johnson began taking daily injections of rapamycin in 2019.
    • Rapamycin is an immunosuppressant drug used to prevent organ rejection after transplants.

    Still unconfirmed:

    • Bryan Johnson's use of supplements and drugs is based on biology but lacks clinical evidence.
    • Max Kennerly endorses the simultaneous use of unregulated medications and implants for tech titans.
    confidence 80%
  3. Tech Titans Use Biohacking to Extend Lifespan

    Entrepreneurs and tech leaders use various biohacking methods to increase their healthspan. These practices vary from evidence-based lifestyle changes to experimental drug use. Some methods remain unproven or are considered hype.

    What's confirmed:

    • Bryan Johnson began taking daily injections of rapamycin in 2019.
    • Biohacking methods range from science-backed changes to unproven experiments.

    Still unconfirmed:

    • Rapamycin is an immunosuppressant drug.
    confidence 80%
  4. Tech Entrepreneur Abandons Rapamycin Trial Due to Side Effects

    Bryan Johnson spent years testing rapamycin to extend his lifespan. He stopped the regimen in September 2024 after experiencing adverse health effects. Biohacking practices range from science-backed lifestyle changes to unproven experimental methods.

    What's confirmed:

    • Bryan Johnson stopped his personal rapamycin trial in September 2024 because the benefits did not outweigh the drawbacks.
    • Johnson tested rapamycin doses of 5-milligram, 6-mg, and 10-mg.
    • Rapamycin is an immunosuppressant drug used to prevent organ rejection after transplants.

    Still unconfirmed:

    • Johnson experienced high glucose levels, skin infections, blood lipid abnormalities, and a higher resting heart rate due to rapamycin.
    confidence 90%
  5. Billionaires Pursue Biohacking for Life Extension

    Ultra-wealthy individuals and influencers are sharing methods to extend their lifespans. Scientists have questioned the benefits of these anti-aging practices. Some efforts include the use of pharmaceuticals to delay aging.

    What's confirmed:

    • Ultra-rich individuals and influencers are exchanging tips and tricks to extend their lifespan.
    • Scientists are questioning the benefits of the anti-aging biohacking boom driven by Silicon Valley billionaires.

    Still unconfirmed:

    • Entrepreneur Bryan Johnson began taking daily injections of the immunosuppressant drug rapamycin in 2019.
    • Russian President Vladimir Putin has plans to live forever.
    confidence 90%